Our lab research is focused on developing cutting-edge computational tools and methods to understand physiology and disease and develop new therapies. Our research spans a wide range of physiological areas and topics, including electrophysiology, cellular and subcellular signaling pathways, and mechanobiology. We study healthy normal physiological functioning and diseases and pathologies, including cardiac arrhythmias, fibrosis, and cancer. In our lab, we use multiscale and stochastic models to study complex physiological phenomena.
Computational modeling is a multidisciplinary field, combining tools from engineering, biology, mathematics, physics, chemistry, and computational science. Over the past few decades, computational modeling has become an invaluable counterpart to experimental physiology and a powerful tool for predictive medicine – using models to understand and predict biological behavior during disease and responses to potential therapies.
3/3/2019 – Madison, Mario, Vrishti, and Shreyas present at the Biophysical Society (BPS) annual meeting in Baltimore, Maryland.
10/18/2018 – Madison and Mario present at the Biomedical Engineering Society (BMES) annual meeting in Atlanta, Georgia.
10/4/2018 - Dr. Weinberg's recent paper with collaborator Dr. Cheng Ly, "Analysis of heterogeneous cardiac pacemaker tissue models and traveling wave dynamics" is published in the Journal of Theoretical Biology.
8/20/2018 - Shreyas and Vrishti join the lab as Ph.D. students and Navpreet joins the lab as an M.S. student. Welcome!
7/3/2018 - Dr. Weinberg presents at the Kavli Institute of Theoretical Physics, Program on Integrative Cardiac Dynamics.
7/1/2018 - Dr. Weinberg and collaborator Dr. Steven Poelzing at Virginia Tech are awarded a 4-year R01 award from the National Institutes of Health!
5/30/2018 - Madison, Mario, Lewis, Tien, and Vrishti present at the Biology and Medicine through Mathematics conference in Richmond, Virginia.
5/24/2018 - Madison, Mario, Vrishti, and Tien present at the Virginia Academy of Science annual meeting in Farmville, Virginia.
3/1/2018 - Dr. Weinberg and Dr. Christopher Lemmon are awarded a 4-year R01 award from the National Institutes of Health!
2/19/2018 - Lewis, Tien, and Vrishti present at the Biophysical Society annual meeting in San Francisco, California.
1/11/2018 - Vrishti and Dr. Weinberg's recent paper, "Heart rate variability alters cardiac repolarization and electromechanical dynamics" was published in the Journal of Theoretical Biology. Congrats Vrishti!
12/22/2017 - Dr. Weinberg's recent paper with Dr. Christopher Lemmon, "Multiple Cryptic Binding are Necessary for Robust Fibronectin Assembly: An In Silico Study," was published in Scientific Reports.